Wednesday, February 8, 2012

What makes a home? A staircase or a fireplace?

Is a home a real home without a fireplace at the centre and a staircase leading to the next floor? When people are looking for homes or designing their own, it is often features like the fireplace and staircase that take a priority in the design, even over sizes of rooms. My parents once bought a home with a large brick circular fireplace with a spiral staircase leading downstairs. It was the first thing people saw when they walked in and they were always remarking about it. For me it was fun to run around!

People often insist on a home having a fireplace, regardless of if it?s functioning or not simply for the look. Fireplaces whether they are made of brick, stone, or some other material always have a way of making a room feel inviting and warm.

Some people don?t mind about a fireplace in the sitting room but they would do anything for an aga cooking system in their kitchen with stone surroundings. Kitchens are often the heart of the home and people relish in having space to cook and prepare food in as well as to spend several hours in good company.

However many can forgive a fireplace or a kitchen not being perfect but will do anything for a classic looking staircase. One that reminds them of something they?ve seen in a period drama. Stone staircases are handcrafted by experts and quite an investment, but are timeless and are often only seen in restored period homes.

Many people have bought a home simply because of the set of stone stairs that spoke of generations past and was flooded with memories. Still others are commissioning stone staircases for modern new build homes, giving them a timeless piece of soul that they are so often missing. Often the rest of the home does not matter so much if there is one stunning centrepiece like a fireplace or stone staircase.

For your next project why not consider Stone Stairs at competetive prices from www.manorhousestone.co.uk

Source: http://www.writers4net.com/family/what-makes-a-home-a-staircase-or-a-fireplace/

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LSUHSC research identifies new prostate cancer drug target | LSU ...

New Orleans, LA ? Research led by Wanguo Liu, PhD, Associate Professor of Genetics at LSU Health Sciences Center New Orleans, has identified a new protein critical to the development and growth of prostate cancer. The findings are published online in the Early Edition of Proceedings of the National Academy of Sciences, available the week of February 6, 2012.

Dr. Liu and his team discovered a protein called ARD1 which is involved with the male hormone, androgen, and its receptor. Prostate cancer is a hormone-regulated disease and the main hormone is androgen. Androgen activates its receptor ? androgen receptor (AR) to play a critical role in the development and progression of prostate cancer. Therefore, androgen deprivation therapy has been a standard treatment for advanced prostate cancer.

?However, a majority of tumors invariably relapse and become an androgen-independent prostate cancer from which most patients eventually die,? notes Dr. Liu, who is also a member of the LSUHSC Stanley S. Scott Cancer Center.

To find an alternative strategy to treat prostate cancer, Dr. Liu?s group is studying androgen receptor activators and increasing levels of these activators leading to prostate cancer. Following the discovery of this new protein, they determined that ARD1 is overproduced in the majority of prostate cancer samples, that it activates the androgen receptor, and that it is an essential component of prostate cancer cell growth.

?In addition, we demonstrated that inactivation of ARD1 inhibits the function of androgen receptors resulting in complete suppression of prostate cancer cell growth in tissue culture and prostate tumor growth in mice,? reports Dr. Liu. ?Furthermore, we revealed that the role of ARD1 in the development of prostate cancer is to modify the androgen receptor to enhance its activity.?

According to the National Cancer Institute, about 242,000 American men will be diagnosed with prostate cancer this year. It is the second most diagnosed cancer among men, only behind skin cancer. An estimated 28,170 men will die from prostate cancer in 2012.

?Our study provides a novel avenue for controlling AR-mediated prostate tumor development by directly inhibiting the function of ARD1 or AR-ARD1 interaction,? says Dr. Liu. ?Developing an ARD1-specific inhibitor or an AR-ARD1 interaction-disrupting compound may be of therapeutic benefit in the treatment of prostate cancer.?

###

The research was supported by grants from the National Institutes of Health, the Louisiana Cancer Research Consortium, and the National Natural Science Foundation of China. The research team also included scientists from Yunnan University in Kunming, China, and the University of Nice in France.

LSU Health Sciences Center New Orleans educates Louisiana?s health care professionals. The state?s academic health leader, LSUHSC consists of a School of Medicine, the state?s only School of Dentistry, Louisiana?s only public School of Public Health, the only School of Nursing within an academic health center in Louisiana, and Schools of Allied Health Professions, and Graduate Studies. LSUHSC faculty take care of patients in public and private hospitals and clinics throughout the region. In the vanguard of biosciences research in a number of areas in a worldwide arena, the LSUHSC research enterprise generates jobs and enormous economic impact. LSUHSC faculty have made lifesaving discoveries and continue to work to prevent, advance treatment, or cure disease. To learn more, visit http://www.lsuhsc.edu and http://www.twitter.com/LSUHSCHealth.

Source: http://www.lsusystem.edu/index.php/2012/02/07/lsuhsc-research-identifies-new-prostate-cancer-drug-target/

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Can We Conceal That Our Home Has Been Re-Listed? | Rock-n ...

questions

Q: Our house has been on the market for approximately six months now. I suggested that we take it off the market and re-list in spring. The house is located in a summer resort area and not many people are there in the winter. Our Realtor said it wouldn?t matter with the listing.

John Q. Public could find out that the listing was taken off and re-listed for up to 5 years. I thought that when you re-list you were assigned a new MLS # and most of that information was only accessible to Realtors. Please help!
?Whoclou, Madison, AL

A: It is market-dependent as to whether MLS shows that information (in my market, it shows days-on-market so if you cancelled and then listed again, it would show only DOM for the new listing).

Ultimately it is your decision (whether you want to freshen it up or just don?t want to deal with showings), but read the listing contract for details as to the time frames. Best of luck.
Alex Cortez is a Realtor? with Wailea Village Properties LLC dba/Island Sotheby?s in Kihei, HI.

A: There is a difference between withdrawn off the market and canceled. Withdrawn means the listing is still listed but not currently being marketed. I suggest you cancel the listing and re-list in spring. This will give a new MLS# and new life to your listing.
Beverly Houlier is a Realtor? with Hilltop Chateau Realty in San Diego, CA.

A: I agree with your Realtor. It won?t be difficult for a prospective buyer to find how long and when you were on the market.
Maria Picardi-Kenyon is a Realtor? with Re/Max Tri County Realtors in Hamilton, NJ

Are you interested in having a qualified REALTOR answer your questions? Click through to Ask a REALTOR? now.

Are you a REALTOR who would like to answer consumer questions? Click through to become an Ask a REALTOR? participant.

Source: http://rock-n-rollrealestateagent.com/can-we-conceal-that-our-home-has-been-re-listed/

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Tuesday, February 7, 2012

The Many Advantages of Owning a Swimming Pool in Your Home











Having a swimming pool in your Chicago home is a smart choice for you and your family. There's nothing like having instant access to cool waters after a long day of stressful work, the feeling of wading and lapping, releasing all your cares away. Having a swimming pool in your home offers many advantages, and here are some of them.

Family Bonding Time

A swimming pool in your Chicago home provides the opportunity for you to bond with your family members in a more interactive way. Sure, you can watch television, dine or read books together, but there's something about swimming that makes it extra special. It is not something you get to do every day, unlike eating together at the dinner table every night. Swimming is relaxing and requires physical effort, as well as the effort to allot a specific time for everyone to gather together and have dip in the pool.

Fun Moments with Friends

A pool also serves as a venue for fun times with friends. Nobody is exempted from enjoying a pool party, what with the laidback vibe it offers and the various activities you can do in a pool, such as games. There are so many pool games to choose from for all ages, whether you are holding a pool party for children or for adults.

Health Benefits

Good health is another benefit enjoyed by homeowners with swimming pools Chicago construction companies build for Chicago homes. Various studies have found that swimming is a great cardio exercise for weight loss because it involves a lot of body parts. Swimming provides the opportunity to keep a trim, muscular body and strong resistance.

For Your Home Value

Having a swimming pool in your Chicago home is a great way to increase your home value. Remember that the more amenities in a house, the higher its value. This will benefit you particularly in the future, when the time comes that you will want to sell your house. When this time comes, you can consult construction companies that remodel inground swimming pool Chicago homes have.

Stress Release

Last but not the least, having a swimming pool in your home can serve as a venue for stress release and relaxation. Exerting a lot of effort just to be able to complete a set of laps is a great way to liberate yourself from various tensions and inhibitions. Having a swimming pool is a smart choice for you and your family. Choose among a variety of pools Chicago construction companies offer.

If you have questions, please visit us at www.sunsetpools-spas.com for complete details and answers.

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Monday, February 6, 2012

Employment Agencies to Search for Jobs | hoosierstc.org

Feb 06 2012

Finding a job is a job itself. If all jobs just fell from the sky, then every one would be employed. However, the reality is that unemployment is at an all time high, and the job market is over-saturated with applicants seeking a new career opportunity. Fortunately, there are employment agencies that help make job searching easier and more convenient. Professional recruiters are hired to help companies find the perfect candidate who matches the job requirements. They also help candidates find the perfect job that matches their job description. Essentially, they are an employment match maker, and they have a lot of useful tools when it comes to helping people find jobs. There are a lot of Columbus Ohio Employment Agencies that can help place you in your next career. Just check your local listings and send your resume to some of their recruiters, who will then search for jobs that are a good fit on both ends.

Source: http://www.hoosierstc.org/business-finance/careers/employment-agencies-to-search-for-jobs

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Syria next steps: With diplomacy stalled, escalation expected (The Christian Science Monitor)

Beirut, Lebanon ? Diplomatic efforts to resolve the crisis in Syria appear to have reached an impasse following the vetoing by Russia and China of a United Nations Security Council resolution.

The vote at the UN Security Council on Saturday came amid the worst surge of violence in Syria since the uprising against the regime of Syrian President Bashar al-Assad began in mid-March last year, with over 300 people reported dead since Friday in the flashpoint city of Homs.

With diplomacy running out of steam, analysts expect the violence in Syria to intensify as an emboldened Mr. Assad redoubles efforts to stamp out the revolt while the opposition steps up acts of civil disobedience and rebel forces continue the shift to armed resistance.

?The situation in Syria is going to escalate with greater bloodshed in the streets as a consequences of the vetoes which ended up giving the regime greater support,? says Imad Salamey, associate professor of politics at the Lebanese American University in Beirut.

Think you know the Middle East? Try our geography quiz.

He added that there would be an increase of diplomatic pressure on Russia and China to reverse its backing for Syria which would likely require even greater concessions from the US, Europe, and the Arab world.

Watered-down resolutionThe draft of the UN Security Council resolution was a watered-down version of the original text presented by Morocco which was based on an Arab League initiative. The Arab League had called for Assad to transfer power to his deputy and for a national unity government to be formed within two months. But the final draft presented for vote on Saturday limited its demands to calling for a cessation of violence and launching a dialogue between the regime and the opposition. Russia has repeatedly warned against UN moves that could set the stage for a military intervention similar to the NATO campaign to support rebels attempting to overthrow former Libyan leader Muammar Qaddafi.

A US official involved in Syria policy described the veto as ???catastrophic??

?We can?t let Moscow and Beijing have the final word on this,? the official says.

Still, it is unclear what further diplomatic opportunities exist. Sergei Lavrov, the Russian foreign minister, is scheduled to visit Damascus Tuesday where, he said, he will press for ?rapid democratic reforms." Assad has promised a raft of political reforms, but implementation has been slow and overshadowed by the worsening violence. Syria blames the uprising on ?foreign conspiracies? and says the violence is being perpetrated by ?armed terrorist gangs.?

Arab League monitoringAn Arab League mission to monitor Syrian compliance with a joint agreement reached in November collapsed last month after several Gulf countries, including Saudi Arabia, withdrew their observers. The mission had been criticized for failing to prevent further violence, but diplomats say that it did succeed in casting an international spotlight on trouble spots that previously had been inaccessible. It also helped reduce the level of violence as the regular Syrian forces were compelled to withdraw troops and armored vehicles, albeit temporarily, from towns and cities. It is unclear whether the Arab League has the will to revive the observer mission or even if Damascus would permit the monitors to return.

?The only thing [the international community] can do now is continue to tighten the sanctions already in place which are biting the Syrian economy, and probably the Arabs and others might be arming the opposition more and more, so playing a long game,? says Paul Salem, director the Carnegie Endowment?s Middle East Center in Beirut. ?This is not going to be resolved by a [single] decision so it?s going to get bloodier.?

The West has balked at playing a more direct military role in Syria, such as establishing and policing safe havens or no-fly zones where refugees and rebel fighters with the Free Syrian Army can congregate. But a diplomatic impasse could encourage logistical support, possibly covert initially, for the FSA or at the very least a more focused assessment of the rebel army?s capabilities.

US Sen. Joe Lieberman (I) of Connecticut said on Sunday that the Syrian rebels should receive a ?range of support? from medical supplies to intelligence and reconnaissance capabilities.

?And then ultimately it is providing them with weapons,? he said during a panel discussion on the Middle East in Munich, Germany.

Rebel ranks swellingThe ranks of the FSA have swelled in recent weeks with deserters from the regular Syrian army and it is claiming responsibility for a growing number of attacks against the Assad regime?s security forces. But the FSA is relatively lightly-armed, with weapons and ammunition in short supply. The FSA?s leadership is in Turkey, but it is unclear what level of control it exerts over military units scattered across the country.

?The FSA should be supported by the international community,? says Jeffrey White, a military analyst at the Washington Institute for Near East Policy. ?This support should be both political and military. The FSA should be recognized as the legitimate armed opposition to the regime.?

Professor Salamey said that the military option of supporting the FSA could be attractive to Turkey which is concerned over stability in areas of Syria adjacent to its border.

?Nevertheless, I believe most domestic forces and players realize that a military confrontation will not help the opposition and may lead to a prolongation of the conflict and give the regime the upper hand,? he says.

The Syrian army remains much stronger than the FSA, despite the wave of desertions from its ranks. The FSA is lightly armed and comparatively small compared to the military which has artillery, armored vehicles, and air power at its disposal giving it an edge in any direct confrontation.

Last week, Syria leaned on Lebanon to tighten its control of their shared border to block the flow of smuggled weapons into Syria and halt the passage of FSA militants and refugees. In response, Lebanese troops have deployed more heavily in the northern Wadi Khaled district which lies only 20 miles from Homs and where Lebanese support for the Syrian opposition runs high.

Think you know the Middle East? Try our geography quiz.

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Source: http://us.rd.yahoo.com/dailynews/rss/un/*http%3A//news.yahoo.com/s/csm/20120205/wl_csm/461844

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Sunday, February 5, 2012

Barbecue Grills Easy methods to Maintain Them Thoroughly clean ...

In the event the climate warms up it?s time to fireplace up the yard barbecue grill and revel in leisurely pleasurable days with the friends and family and pals. Foodstuff just appears to be to style considerably better when it will be geared up on the grill, it doesn?t matter what is over the menu. Summertime and barbecues go hand in hand.

Identical to you absolutely need to maintain your kitchen area stove in wonderful performing purchase, you additionally will need to the right way take care of your barbecue grill to ensure it stays clear as well as in really good problem. Below certainly are a couple of ideas in your case to consider when it happens time for you to cleanse your barbecue.

Right before cleansing your bbq grill, make sure you learn the instruction handbook that arrived with it any time you very first acquired it. Your explicit barbecue cooking grill would possibly have some do?s or don?ts that you just needs to be mindful of.

Such as, some barbecue grills include a guarantee. You would like to make certain that you won?t be performing nearly anything to destruction the grill with the function that it could void the guarantee.

If the grill won?t have precise guidelines regarding how to cleanse it, then you definately can abide by these standard recommendations to cleansing a barbecue grill. First of all, you might want to devote inside of a really good grill brush, ideally one which is produced with brass bristles. Make use of this brush in the grill grate to operate free any stuck-on meals.

At the time the food items particles happen to be loosened up, rinse them from the grill with very hot drinking water. In the event the foods buildup is especially stubborn, you are able to include a fantastic grease preventing dish soap to your scorching h2o. It may additionally support to make use of a h2o hose for rinsing considering the fact that the large strain should help eradicate trapped Portable Kitchen PK 99740. on foods.

With the party that you simply are not able to wholly clear the grate, there exists a way of burning off the particles that may be completed. Quickly destination aluminum foil about the grate, then convert off the grill. This will likely allow for warmth to get trapped in along with the metallic grate. Permit the grill neat down then eradicate the foil. Rinse the rest in the free foodstuff off with drinking water.

Some other suggestion to maintain in intellect is the fact that soon after you happen to be achieved grilling, the grate would be the simplest to wash. This is often related on the ?burn off? way during the very last phase. Just make sure to wait around right up until the grate has cooled off more than enough to the touch, after which scrub it less than sizzling, soapy h2o.

One more suggestion to maintain in intellect is always that you may spray your grill that has a non-stick cooking spray such as you use when cooking with your cooking area. Designed to guide maintain foods from sticking so cleanse up time goes a lot faster. Cleansing a barbecue grill may very well be wearisome in particular should you make it possible for dried meals to develop up. A cleanse grill can be a whole lot far more sanitary and can be simpler available for you to deliver the results with. If you happen to thoroughly clean Char-broil Quantum Urban. your Barbecue grill soon after each individual use you will definitely be cleansing a lot less as well as your grill can be wanting to go at any time when you want Chargriller Duo 5050. it.

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Source: http://www.donkonstante.com/barbecue-grills-easy-methods-to-maintain-them-thoroughly-clean-for-balanced-foods-preparing-and-cooking/

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